Medications : Trisul Paediatric Sugar Free (Trimethoprim/Sulfamethoxazole)

TRISUL should only be used where, in the judgement of the physician, the benefits of treatment outweigh any possible risks; consideration should be given to the use of a single effective antibacterial agent. The in vitro susceptibility of bacteria to antibiotics varies geographically and with time; the local situation should always be considered when selecting antibiotic therapy.Urinary tract infectionsTreatment of acute uncomplicated urinary tract infections. It is recommended that initial episodes of uncomplicated urinary tract infections be treated with a single effective antibacterial agent rather than the combination.Respiratory tract infectionsTreatment of otitis media. TRISUL is not indicated for prophylactic or prolonged administration in otitis media.Treatment of acute exacerbations of chronic bronchitis.Treatment and prevention of Pneumocystis Jirovecii. (See Dosage and Administration and Adverse Effects).Other bacterial infections caused by sensitive organismsThere are a number of other bacterial infections caused by sensitive organisms for which treatment with TRISUL may be appropriate; the use of TRISUL in such conditions should be based on clinical experience and local in vitro data.Treatment and prophylaxis of toxoplasmosis, treatment of nocardiosis.Dosage and AdministrationIt may be preferable to take TRISUL with some food or drink to minimise the possibility of gastrointestinal disturbances.Acute InfectionsChildren aged 12 years and underAge Paediatric Suspension 6 to 12 years 10 ml every 12 hours 6 months to 5 years 5 ml every 12 hours 6 weeks to 5 months 2.5 ml every 12 hours This dosage approximates to 6 mg trimethoprim and 30 mg sulfamethoxazole per kilogram body weight per 24 hours.Treatment should be continued until the patient has been symptom free for two days; the majority will require treatment for at least 5 days. If clinical improvement is not evident after 7 days' therapy, the patient should be reassessed.As an alternative to STANDARD DOSAGE for acute uncomplicated lower urinary tract infections, short term therapy of 1 to 3 days' duration has been shown to be effective.

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